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ACTA Pharmaceutica Sciencia
2024 , Vol 62 , Num 4
Determination of essential oil compositions as well as phenolic and flavonoid contents of Inula viscosa L. and Inula graveolens L. from the coastal region of Latakia - Syria
1 Tishreen University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry and Drug Control, Latakia, Syria2 Tishreen University, Faculty of Pharmacy, Department of Pharmacology, Latakia, Syria
3 Tishreen University, Faculty of Pharmacy, Department of Pharmacognosy, Latakia, Syria
DOI : 10.23893/1307-2080.APS6260 Viewed : 4087 - Downloaded : 3551 The essential oils (EOs) of dry leaves of Inula viscosa L. and Inula graveolens L. obtained by hydro-distillation were investigated using GC-MS within two different harvest seasons, namely summer and autumn (August and October, respectively). The results showed that the essential oils were mainly composed of monoterpenes and sesquiterpenes. Twenty-four and fifty active components, representing 63.22% and 85.41% of the essential oils, were identified in I. viscosa L., whereas, fifty-two and thirty-five active components, representing 96.46% and 58.26% of the essential oils, were identified in I. graveolens L throughout the two harvest seasons respectively. The quantitative determination of methanolic extracts of I. viscosa L. and I. graveolens L. leaves was performed, where the total phenolic contents (TPC) and total flavonoid contents (TFC) were measured. Methanolic extracts of I. viscosa L. were found to be richer in phenolic and flavonoid contents than those of I. graveolens L. in the two considered seasons. Keywords : medical plants, essential oil, phenolic content, flavonoid content, harvest season