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ACTA Pharmaceutica Sciencia 2023 , Vol 61 , Num 2
Bioautography for evaluation of several Lavandula L. and Origanum species antimicrobial and antioxidant activity
Şule Nur KARAVUŞ 1-2 Ayşegül ÇAŞKURLU 1-2 Ayşe Esra KARADAĞ 1-3 Fatih DEMİRCİ 3
1 Department of Pharmacognosy, Faculty of Pharmacy, İstanbul Medipol University, İstanbul, Türkiye
2 Institute of Health Sciences, İstanbul University, İstanbul, Türkiye
3 Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir, Türkiye
DOI : 10.23893/1307-2080.APS6110 In the search of bioactive natural compounds, bioautography of plant extracts were associated in an antioxidant screening. Due to containing variety of phenolic compounds Lavandula and Origanum species are important medicinal plants. The antioxidant and free radical scavenging activities of Lavandula angustifolia, L. stoechas, L. heterophylla, Origanum majorana, O. onites, O. vulgare, O. minituflorum, and their main phenolic compounds linalool and carvacrol was carried out by TLCbioautography method based on the DPPH· and ABTS·+ assays to compare essential oils and known main active constituents. The antimicrobial activity of the materials was tested using the in vitro broth microdilution assay towards two different microorganisms. Methicillin-resistant Staphylococcus aureus and Streptococcus mutans were used for the study. As a result of our studies, it is determined that O. vulgare showed the highest activity against S. mutans and O. onites and O. vulgare showed the highest activity against MRSA. compared to the tested antibiotic. Keywords : Lavandula, Origanum, essential oil, bioautography, antioxidant

Istanbul Medipol University