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ACTA Pharmaceutica Sciencia 2022 , Vol 60 , Num 2
Cytotoxic activity of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin
Fatma TOSUN 1 Mahmut MISKI 2
1 Department of Pharmacognosy, School of Pharmacy, Istanbul Medipol University, Istanbul, Turkey
2 Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey
DOI : 10.23893/1307-2080.APS.6009 Cytotoxic activities of the fruit extracts of Heptaptera anatolica (Boiss.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. anatolica showed the best cytotoxic activities with IC50 values of 17.9 and 15.1 ug/mL on the COLO205 and KM12 cell lines, respectively. Whereas, the ethyl acetate extract of the fruits showed moderate cytotoxic activity with IC50 values of 23.4 ug/mL against the KM12 cell lines. Keywords : Cytotoxic activity, Heptaptera anatolica, Apiaceae

Istanbul Medipol University