| Submission to first decision
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3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2021 , Vol 59 , Num 4
Relationship Between Interleukin 33 and Tissue Factor in Non-Diabetic and Diabetic Obese Patients
1 Department of Biochemistry, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey2 Department of Clinical Biochemistry, Cekirge Devlet Hastanesi, Bursa, Turkey
3 Departmant of Department of Biostatistics and Medical Informatics, Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey
DOI : 10.23893/1307-2080.APS.05934 Viewed : 18540 - Downloaded : 4426 The aim of the study is to investigate the relationship between tissue factor (TF) and Interleukin-33 (IL-33) and biochemical parameters in diabetic obese and non-diabetic obese patients. 21 healthy controls, 25 non-diabetic and 36 diabetic-obese patients were included in the study. While there was no difference between the groups in terms of IL-33 levels (p> 0.05), TF levels of diabetic obese group were statistically significantly higher than control group (p <0.05). HDL levels of the obese and diabetic obese groups were significantly lower than control group, and triglyceride, glucose, insulin, C-reactive protein (CRP), hemoglobin A1c (HbA1c), and HOMA-IR levels were significantly higher (p <0.05). A positive correlation was found between TF activity, and HbA1c and glucose levels (p <0.05). This suggests that TF may be predictive for diabetes which develop in the background of obesity, and that TF can be used as a prognostic value for diabetes. Keywords : Diabetes Mellitus, interleukin 33, obesity, tissue factor