| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2007 , Vol 49 , Num 3
FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE DOSAGE FORM OF ACETAZOLAMIDE
Department of Pharmacy, Annamalai University, Annamalainagar – Chidambaram (Tamil Nadu), INDIA
Viewed :
19531
-
Downloaded :
47
Acetazolamide sustained release (S.R.) capsule 500 mg was prepared according to release pattern suggested by Wagner (1971). Comparative release pattern of the drug from S.R. pellets by using glyceryl monostearate, microcrystalline wax and microcrystalline wax and glyceryl distearate was studied. 00 hard gelatin capsule filled with combination of 35% of drug coated pellets (DC) and 65% of DC with 1:1 ratio of microcrystalline wax and glyceryl distearate on basis of drug content was successful and found stable in evaluations. Application of various kinetic equations to in vitro data indicated biphasic zero order release.
Keywords :
ACETAZOLAMIDE 500 MG, SUSTAINED RELEASE, CAPSULE, IN VITRO