Acceptance rate 46%
Time to first decision 6 months*
Time to decision with review 50 days*

*Approximate number of days

**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.


ACTA Pharmaceutica Sciencia 2007 , Vol 49 , Num 1
CHEMOMODULATORY INFLUENCE OF CISSAMPELOS PAREIRA (L.) HIRSUTA ON GASTRIC CANCER AND ANTIOXIDANT SYSTEM IN EXPERIMENTAL ANIMAL
G AMRESH, R KANT, V RAO, P N SİNGH
Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, (Council of Scientific and Industrial Research) Rana Pratap Marg, Uttar Pradesh, India Viewed : 17078 - Downloaded : 5143 The objective of the present study was to investigate the protective effect of ethanolic extract of Cissampelos pareira (CPE) against gastric cancer and its mode of action. The bioassay-guided fractionation of the CPE yielded a compound, identified as 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one (Quercetin) with the help of NMR and various spectrophotometer methods as U.V., I.R. and other chemical tests. The protective effects of C. pareira were studied against Benzo(a)pyrene (B(a)P) induced gastric cancer, tumor multiplicity, micronucleus polychromatic erythrocytes (MnPCEs) in mice. The effect of CPE on SOD, CAT, LPO and GST, GPx, GSH was also studied. Keywords : CISSAMPELOS PAREIRA, QUERCETIN, GASTRIC CANCER, MICRONUCLEUS POLYCHROMATIC ERYTHROCYTES

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