| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2022 , Vol 60 , Num 1
Histological effect of traditional rose ointment application in the excisional wound model
1 Histology and Embryology Department, Faculty of Medicine, İstanbul, Turkey2 Medical History and Ethics Department, Faculty of Medicine, İstanbul, Turkey
DOI : 10.23893/1307-2080.APS.6003 Viewed : 16322 - Downloaded : 5160 The aim of our study was to evaluate the histological effects of traditional rose ointment application on artificially induced skin wound treatments. 18 adult BALB/c mice were artificially wounded by the formation of a puncture-generated exhaled wound model. Wound tissues of mice were analyzed histologically with light microscopy after hematoxylin eosin and Masson trichrome stainings were performed. Vascular endothelial growth factor (VEGF) expressions were evaluated by immunohistochemical analysis in order to demonstrate the angiogenesis throughout the tissue. Tissue regeneration rate was significantly increased in traditional rose ointment treated group although there was no significant difference in granulation and angiogenesis between the groups. Traditional rose ointment treatment seems to have a positive effect in the treatment of skin wound by inducing the regeneration capacity in the tissue. Further studies are needed to confirm this finding and to evaluate its potential to be used in wound healing. Keywords : Phytotherapy, Wound Healing, Rosa damascena, Histology, Rats