ACTA Pharmaceutica Sciencia 2020 , Vol 58 , Num 2
Ethanolic Whole Plant Extract of Farsetia Jacquemontii Showed Antipyretic & Analgesic Potential in Mice
Neelanchal Trivedi 1 Bhuvnesh Singh 1 K. K. Jha 1
1 Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India
DOI : 10.23893/1307-2080.APS.05814 To evaluate the analgesic and antipyretic activities of ethanolic whole plant extract of Farsetia jacquemontii (EWFJ) in mice. The plant is the habitat of Rajasthan & Northwestern parts of India. In folk system of medicine, it is known as "Faridbooti", used traditionally in rheumatism, constipation, piles & abdominal pain. Antipyretic activity was assessed against Brewer"s yeast induced pyrexia in mice using paracetamol (100 mg/kg) as standard. Analgesic activity was determined against hot plate & acetic acid induced writhing method in mice using diclofenac sodium (10 mg/kg) as standard. EWFJ (400 mg/kg) showed significant antipyretic effect after 2 hours of treatment when compared with standard paracetamol (100 mg/kg) in Brewer"s yeast induced pyrexia model. EWFJ (400 mg/kg) reduced reaction time after 3 hours of treatment in the same manner as with standard diclofenac sodium (10 mg/kg) against hot plate method. EWFJ (400 mg/kg) showed the effect in similar manner as diclofenac sodium (10 mg/kg) against acetic acid induced writhing test. The study concluded antipyretic & analgesic effect of Farsetia jacquemontii. Keywords : Antipyretic, Analgesic, Farsetia jacquemontii

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