| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2025 , Vol 63 , Num 3
Characterization of drug-related problems in gram-negative bloodstream infections with clinical pharmacist input - a prospective study
1 Istanbul Medipol University, School of Medicine, Department of Infectious Diseases and Clinical Microbiology, Istanbul, Tu?rkiye2 Istanbul Medipol University, Graduate School of Health Sciences, Department of Clinical Pharmacy, Istanbul, Türkiye
3 Istanbul Medipol University, Regenerative and Restorative Medicine Research Center (REMER), Research Institute for Health Sciences and Technologies (SABITA), Istanbul, Tu?rkiye
DOI : 10.23893/1307-2080.APS6338 Viewed : 27 - Downloaded : 12 Patients with Gram-negative bacilli bloodstream infections (GNB-BSIs) have a high mortality and morbidity rate. This can result in an increased length of hospitalizations and risk of polypharmacy. This study investigates drug-related problems (DRPs) and associated factors during antimicrobial treatment in GNB-BSI patients. The prospective observational study was conducted between April 2023 and April 2024 at a 970-bed tertiary care university hospital in Istanbul. The study included 150 adult patients with a mean age of 58 years, and 57.3% of patients were male. Multivariable logistic regression analysis highlighted significant associations between DRPs and the presence of comorbidities, the duration of the patient"s hospitalization, time to adequate antimicrobial therapy and the number of prescribed medications per patient (p<0.05). In conclusion, this study underscores the significance of clinical pharmacists" collaboration with clinicians in the identification and assessment of drug-related problems (DRPs) within the clinical department. Keywords : bloodstream infections, gram-negative bacteria, drug-related problems, antibiotic stewardship, clinical pharmacist