| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2024 , Vol 62 , Num 3
Thermosensitive gel of pomegranate peel extract as alternative for the treatment of local infections
1 Bilecik Seyh Edebali University, Vocational School of Health Services, Department of Pharmacy Services, Bilecik, Türkiye2 Bilecik Seyh Edebali University, Faculty of Engineering, Department of Bioengineering, Bilecik, Türkiye
3 Bilecik Seyh Edebali University, Graduate School of Education, Department of Biotechnology, Bilecik, Türkiye
4 Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Eskisehir, Türkiye
DOI : 10.23893/1307-2080.APS6241 Viewed : 4286 - Downloaded : 1632 Studies on the use of herbal extracts in the treatment of local diseases are increasing day by day. To maintain activity of extract and provide convenient usage, ideal formulation must be developed for extracts. In this study, we aimed to develop thermosensitive gel of pomegranate peel extract and investigate its antimicrobial activity. The total phenolic content and antioxidant capacity of extract was found 397.00 ± 9.36 mg GAE/100 g, and 10750.00 ± 132.29 mg TE/100 g respectively. The gelation temperature of thermosensitive was measured as 25.3 ± 1.5?C. The developed gel formulation showed antimicrobial activity against Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans as similar with extract. As a result, the developed thermosensitive gel formulation of pomegranate peel extract could be an alternative for the treatment of local infections by its ease of usage and efficacy in future clinical trials after detailed characterization. Keywords : pomegranate peel, extract, thermosensitive gel, antimicrobial activity