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ACTA Pharmaceutica Sciencia
2021 , Vol 59 , Num 4
The Study of Phenolic Compounds and Antioxidant Activity of Raw Materials of Reynoutria Sachalinensis (F. Schmidt) Nakai
1 Department of Chemistry of Natural Compounds and Nutritiology, National University of Pharmacy, Kharkiv, UkraineDOI : 10.23893/1307-2080.APS.05933 Viewed : 19015 - Downloaded : 5406 Phenolic composition and quantitative evaluation of herbal part and root extracts for Reynoutria sachalinensis studied by HPLC method. Using the same method, we also established the antioxidant activity of R. sachalinensis raw materials. Six phenolic compounds were idenified for herbal part of R. sachalinensis as, gallic acid, chlorogenic acid, trans-cinnamic acid, rutin, hyperoside and isoquercitrin at total amount of 885.37±21.25 mg/kg. Neochlorogenic acid and rutin were found as main compounds for herbal part of R. sachalinensis, and gallic acid and 6,7-dihydroisoflavone were determined for root of R. sachalinensis. In R. sachalinensis roots we found gallic acid and 6,7-dihydroisoflavone.
The HPLC study of antioxidant activity showed almost identical antioxidant potential of bioactive substances (BASs) in R. sachalinensis herbal parts and roots that is 3.85±0.09 and 3.59±0.09 mg/g in Trolox equivalent respectively.
The obtained data proved the feasibility of new antioxidant drugs development on the basis of R. sachalinensis raw materials.
Keywords : Reynoutria sachalinensis, phenolic compounds, HPLC