| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2021 , Vol 59 , Num 3
Physical Performance Enhancing Effects of The Aqueous Extract of Alysicarpus Ovalifolius in Mice
1 Department of Pharmacology and Toxicology2 Department of Medicinal Plants Research and Traditional Medicine
DOI : 10.23893/1307-2080.APS.05930 Viewed : 17480 - Downloaded : 5078 Alysicarpus ovalifolius (fabaceae) is an herb used as ingredient of tea that is consumed as a tonic in Northern Nigeria. This study evaluated effects of aqueous extract of the aerial parts of Alysicarpus ovalifolius (AO) on physical performance in Swiss albino mice. Phytoconstituents were identified by HPLC. Performance was assessed by exhaustive swim, rotarod, four limb-hanging and hypoxia test. Effects on diazepam-induced sleep was also evaluated. HPLC detected presence of caffeic (60.34%) and chlorogenic acids (3.44%) and rutin (0.19%). The extract (100 ? 400mg/kg) produced significant (p<0.05) dose-dependent increase in swimming time; increased time spent on the rotarod and also increased duration in the fourlimb hanging test. No significant effect was observed in endurance to hypoxic condition. Diazepam-induced sleeping time was significantly decreased in AO-treated animals. These observations were comparable to caffeine (15mg/kg). The aqueous extract of Alysicarpus ovalifolius increased physical performance in mice by enhancing endurance, muscle strength and co-ordination. Keywords : Alysicarpus ovalifolius, endurance, swim, muscle strength