| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
2 Institue of Health Science, Drug Research and Pharmacokinetic Development and Applied Center, Izmir, Turkey
DOI : 10.23893/1307-2080.APS.05706 Viewed : 18971 - Downloaded : 10055 In this study, the compounds that contain active ingredients beneficial for health and disposed from t he fruits of milk thistle which from oil was extracted after cold press was obtained, and end products were provided.
At this stage, total ash, insoluble ash in HCl, loss on drying, foreign matter, heavy metal and microbiology analyses were carried out on the milk thistle waste supplied as seeds. The seeds were treated to cold press, then oil and waste were obtained. Peroxide value, FFA, refractive index, fatty acid composition, saponification and iodine number were investigated in the oil. The waste had silymarin compounds signi?cantly, therefore verification was performed for the quantitation of silymarin active ingredient in the waste. The waste contained up to 2% silymarin.
As a result, a formulation was created for the standardized active ingredient and milk thistle oil, and end product was provided in the form of soft capsule.
Keywords : cold press, milk thistle (Silybum marianum), silymarin, soft capsule