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ACTA Pharmaceutica Sciencia
2007 , Vol 49 , Num 2
INFLUENCE OF YOGASANAS ON THE PHYSIOLOGY, THERAPY AND THEOPHYLLINE PHARMACOKINETICS IN BRONCHIAL ASTHMA PATIENTS
University College of Pharmaceutical Sciences, Kakatiya University Warangal. Andhra Pradesh. India
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Bronchial asthma is one of the commonest diseases of concern to medical and allied professionals, affecting 5-10% of the general population. Various therapeutic approaches being practiced in the management of bronchial asthma aim at symptomatic level rather than curative. Long term pharmacotherapy has been associated with higher risks of increased severity, adverse reactions, frequency of attacks and increased medication requirements. The three-fold limitations of the treatment procedure in vogue demand the promotion of a heritage, yoga practices on war-footed basis. Our studies reassess the asthmatic to lead a very happy, comfortable and productive life. Physiological parameters such as pulse rate, respiratory rate, breath holding time and general health were found to be significant in the training period of 30 days and could be explained on the basis of the improvised neurohumoral and psychological controls. Influence of thirty days of practice of yogasanas on the disposition of pharmacokinetics of theophylline SR (200mg) was taken and biological half-life was found to be less in the yoga group than in the non-yoga group.
Keywords :
BRONCHIAL ASTHMA, YOGASANAS, THEOPHYLLINE, PHARMACOKINETICS